Assessment of P‐Glycoprotein Substrate and Inhibition Potential of Test Compounds in MDR1‐Transfected MDCK Cells-Reference-Cited by-同舟云学术

Assessment of P‐Glycoprotein Substrate and Inhibition Potential of Test Compounds in MDR1‐Transfected MDCK Cells

Published:2012-09 Issue:1 Volume:58 Page:
ISSN:1934-8282
Container-title:Current Protocols in Pharmacology
language:en
Short-container-title:Current Protocols in Pharmacology

Author:

C. L. Lam Kevin¹,Rajaraman Ganesh¹

Affiliation:

1. NoAb BioDiscoveries, Mississauga Ontario Canada

Publisher

Wiley

Subject

General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/0471141755.ph0713s58

Reference9 articles.

1. The Drug Transporter−Metabolism Alliance: Uncovering and Defining the Interplay

2. European Medicines Agency(2010).Guideline on the Investigation of Drug Interactions.http://www.ema.euorpa.eu.

3. FDA Guidance for the Industry(2012).Drug interaction studies Study design data analysis and implications for dosing and labeling recommendations. U.S. Department of Health and Human Services Food and Drug Administration.http://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/UCM292362.pdf.

4. Membrane transporters in drug development

5. MDCK (Madin-Darby Canine Kidney) Cells: A Tool for Membrane Permeability Screening

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