Long‐term effects of Na + /Ca 2+ exchanger inhibition with ORM‐11035 improves cardiac function and remodelling without lowering blood pressure in a model of heart failure with preserved ejection fraction-Reference-Cited by-同舟云学术

Long‐term effects of Na + /Ca 2+ exchanger inhibition with ORM‐11035 improves cardiac function and remodelling without lowering blood pressure in a model of heart failure with preserved ejection fraction

Published:2019-11-24 Issue:12 Volume:21 Page:1543-1552
ISSN:1388-9842
Container-title:European Journal of Heart Failure
language:en
Short-container-title:Eur J Heart Fail

Author:

Primessnig Uwe¹²³⁴,Bracic Taja²,Levijoki Jouko⁵,Otsomaa Leena⁵,Pollesello Piero⁵,Falcke Martin⁶⁷,Pieske Burkert¹³⁴,Heinzel Frank R.¹³

Affiliation:

1. Department of Internal Medicine and CardiologyCharité – Universitätsmedizin Berlin, Campus Virchow‐Klinikum Berlin Germany

2. Department of CardiologyMedical University of Graz Graz Austria

3. DZHK (German Centre for Cardiovascular Research), Partner Site Berlin Germany

4. Berlin Institute of Health (BIH) Berlin Germany

5. Critical CareOrion Pharma Espoo Finland

6. Max Delbrück Center for Molecular Medicine Berlin Germany

7. Department of PhysicsHumboldt Universität Berlin Germany

Funder

Ludwig Boltzmann Institute for Translational Heart Failure Research

PhD Programme Molecular Medicine of the Medical University of Graz

Publisher

Wiley

Subject

Cardiology and Cardiovascular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ejhf.1619

Reference28 articles.

1. New strategies for heart failure with preserved ejection fraction: the importance of targeted therapies for heart failure phenotypes

2. Novel pathomechanisms of cardiomyocyte dysfunction in a model of heart failure with preserved ejection fraction

3. Rats with moderate renal failure show capillary deficit in heart but not skeletal muscle

4. Intracellular Dyssynchrony of Diastolic Cytosolic [Ca 2+ ] Decay in Ventricular Cardiomyocytes in Cardiac Remodeling and Human Heart Failure

5. JTV519 (K201) reduces sarcoplasmic reticulum Ca2+leak and improves diastolic functionin vitroin murine and human non-failing myocardium

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