HyperSLICE: HyperBand optimized spiral for low‐latency interactive cardiac examination

Author:

Jaubert Olivier1ORCID,Montalt‐Tordera Javier1,Knight Daniel12,Arridge Simon3,Steeden Jennifer1ORCID,Muthurangu Vivek1

Affiliation:

1. UCL Center for Translational Cardiovascular Imaging University College London London UK

2. Department of Cardiology Royal Free London NHS Foundation Trust London UK

3. Department of Computer Science University College London London UK

Abstract

AbstractPurposeInteractive cardiac MRI is used for fast scan planning and MR‐guided interventions. However, the requirement for real‐time acquisition and near‐real‐time visualization constrains the achievable spatio‐temporal resolution. This study aims to improve interactive imaging resolution through optimization of undersampled spiral sampling and leveraging of deep learning for low‐latency reconstruction (deep artifact suppression).MethodsA variable density spiral trajectory was parametrized and optimized via HyperBand to provide the best candidate trajectory for rapid deep artifact suppression. Training data consisted of 692 breath‐held CINEs. The developed interactive sequence was tested in simulations and prospectively in 13 subjects (10 for image evaluation, 2 during catheterization, 1 during exercise). In the prospective study, the optimized framework—HyperSLICE— was compared with conventional Cartesian real‐time and breath‐hold CINE imaging in terms quantitative and qualitative image metrics. Statistical differences were tested using Friedman chi‐squared tests with post hoc Nemenyi test (p < 0.05).ResultsIn simulations the normalized RMS error, peak SNR, structural similarity, and Laplacian energy were all statistically significantly higher using optimized spiral compared to radial and uniform spiral sampling, particularly after scan plan changes (structural similarity: 0.71 vs. 0.45 and 0.43). Prospectively, HyperSLICE enabled a higher spatial and temporal resolution than conventional Cartesian real‐time imaging. The pipeline was demonstrated in patients during catheter pull back, showing sufficiently fast reconstruction for interactive imaging.ConclusionHyperSLICE enables high spatial and temporal resolution interactive imaging. Optimizing the spiral sampling enabled better overall image quality and superior handling of image transitions compared with radial and uniform spiral trajectories.

Funder

British Heart Foundation

Heart Research UK

UK Research and Innovation

Publisher

Wiley

Subject

Radiology, Nuclear Medicine and imaging

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