Phosphomimetic Mutation Destabilizes the Central Core Domain of Human p53-Reference-Cited by-同舟云学术

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Phosphomimetic Mutation Destabilizes the Central Core Domain of Human p53

Published:2018-08-30 Issue:10 Volume:70 Page:1023-1031
ISSN:1521-6543
Container-title:IUBMB Life
language:en
Short-container-title:IUBMB Life

Author:

Luwang Johnson Wahengbam¹,Natesh Ramanathan¹^ORCID

Affiliation:

1. School of Biology; Indian Institute of Science Education and Research Thiruvananthapuram; Thiruvananthapuram-695551 Kerala India

Funder

Indian Insitute of Science Education and Research Thiruvananthapuram

Indian Institute of Science

University of Oxford

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Genetics,Molecular Biology,Biochemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/iub.1914/fullpdf

Reference19 articles.

1. Mutant p53 in cancer: accumulation, gain-of-function, and therapy;Yue;J. Mol. Biol.,2017

2. The tumor suppressor p53: from structures to drug discovery;Joerger;Cold Spring Harb. Perspect. Biol.,2010

3. The p53 tetramer shows an induced-fit interaction of the C-terminal domain with the DNA-binding domain;D'Abramo;Oncogene,2016

4. Structural basis of DNA recognition by p53 tetramers;Kitayner;Mol. Cell,2006

5. Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations;Cho;Science,1994

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Design and Characterization of Mutated Variants of the Oncotoxic Parvoviral Protein NS1;Viruses;2023-01-11

2. Stability of p53 oligomers: Tetramerization of p53 impinges on its stability;Biochimie;2021-10

3. p53 Phosphomimetics Preserve Transient Secondary Structure but Reduce Binding to Mdm2 and MdmX;Biomolecules;2019-03-02

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