Biodistribution of the Multidentate Hydroxypyridinonate Ligand [14C]-3,4,3-LI(1,2-HOPO), a Potent Actinide Decorporation Agent-Reference-Cited by-同舟云学术

Biodistribution of the Multidentate Hydroxypyridinonate Ligand [14C]-3,4,3-LI(1,2-HOPO), a Potent Actinide Decorporation Agent

Published:2015-04-06 Issue:3 Volume:76 Page:107-122
ISSN:0272-4391
Container-title:Drug Development Research
language:en
Short-container-title:Drug Dev. Res.

Author:

Choi Taylor A.¹,Endsley Aaron N.²,Bunin Deborah I.²,Colas Christophe²,An Dahlia D.¹,Morales-Rivera Joel A.¹,Villalobos Jonathan A.¹,Shinn Walter M.²,Dabbs Jack E.²,Chang Polly Y.²,Abergel Rebecca J.¹

Affiliation:

1. Chemical Sciences Division; Lawrence Berkeley National Laboratory; Berkeley CA USA

2. Biosciences Division; SRI International; Menlo Park CA USA

Funder

National Institute of Allergy and Infectious Diseases

Publisher

Wiley

Subject

Drug Discovery

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/ddr.21246/fullpdf

Reference20 articles.

1. Biomimetic actinide chelators: an update on the preclinical development of the orally active hydroxypyridonate decorporation agents 3,4,3-LI(1,2-HOPO) and 5-LIO(Me-3,2-HOPO);Abergel;Health Phys,2010

2. Multidentate terephthalamidate and hydroxypyridonate ligands: Towards new orally active chelators;Abergel;Hemoglobin,2011

3. Efficacy and safety toxicology of hydroxypyridinonate actinide decorporation agents in rodents: Towards a safe and effective human dosing regimen;Bunin;Rad Res,2013

4. Medical countermeasures against nuclear threats: Radionuclide decorporation agents;Cassatt;Rad Res,2008

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