Childhood BMI trajectories predict cardiometabolic risk and perceived stress at age 13 years: the STARS cohort

Author:

Chen Yun1ORCID,Dangardt Frida23ORCID,Gelander Lars4,Friberg Peter1

Affiliation:

1. School of Public Health and Community Medicine Institute of Medicine, Sahlgrenska Academy, University of Gothenburg Gothenburg Sweden

2. Paediatric Heart Centre The Queen Silvia Children's Hospital, Sahlgrenska University Hospital Gothenburg Sweden

3. Department of Molecular and Clinical Medicine Institute of Medicine, Sahlgrenska Academy, University of Gothenburg Gothenburg Sweden

4. Department of Physiology/Endocrinology, Institute of Neuroscience & Physiology, Sahlgrenska Academy University of Gothenburg Gothenburg Sweden

Abstract

AbstractObjectiveThe aim of this study was to examine BMI trajectories from birth throughout childhood, associations with health outcomes at age 13 years, and time frames during which early‐life BMI influenced adolescent health.MethodsParticipants (1902, 44% male) reported perceived stress and psychosomatic symptoms and were examined for waist circumference (WC), systolic blood pressure (SBP), pulse wave velocity, and white blood cell counts (WBC). BMI trajectory was analyzed using group‐based trajectory modeling of retrospective data of weight/height from birth throughout childhood. The authors performed linear regression to assess associations between BMI trajectories and health outcomes at age 13 years, presented as estimated mean differences with 95% CI among trajectories.ResultsThree BMI trajectories were identified: normal; moderate; and excessive gain. Adjusting for covariates, adolescents with excessive gain had higher WC (19.2 [95% CI: 18.4–20.0] cm), SBP (3.6 [95% CI: 2.4–4.4] mm Hg), WBC (0.7 [95% CI: 0.4–0.9] × 109/L), and stress (1.1 [95% CI: 0.2–1.9]) than adolescents with normal gain. Higher WC (6.4 [95% CI: 5.8–6.9] cm), SBP (1.8 [95% CI: 1.0–2.5] mm Hg), and stress (0.7 [95% CI: 0.1–1.2]) were found in adolescents with moderate versus normal gain. The association of early‐life BMI with SBP started around age 6 years with the excessive gain group, which was earlier than in the normal and moderate gain groups, in which it started at age 12 years.ConclusionsAn excessive gain BMI trajectory from birth predicts cardiometabolic risk and stress in 13‐year‐old individuals.

Funder

Vetenskapsrådet

Forskningsrådet om Hälsa, Arbetsliv och Välfärd

Västra Götalandsregionen

Carl Bennet AB

Publisher

Wiley

Subject

Nutrition and Dietetics,Endocrinology,Endocrinology, Diabetes and Metabolism,Medicine (miscellaneous)

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3