Development of a robust nitrilase by fragment swapping and semi‐rational design for efficient biosynthesis of pregabalin precursor-Reference-Cited by-同舟云学术

Development of a robust nitrilase by fragment swapping and semi‐rational design for efficient biosynthesis of pregabalin precursor

Published:2019-11-12 Issue:2 Volume:117 Page:318-329
ISSN:0006-3592
Container-title:Biotechnology and Bioengineering
language:en
Short-container-title:Biotechnology and Bioengineering

Author:

Zhang Qin¹²,Lu Xia‐Feng¹²,Zhang Yan¹²,Tang Xiao‐Ling¹²,Zheng Ren‐Chao¹²^ORCID,Zheng Yu‐Guo¹²^ORCID

Affiliation:

1. Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and BioengineeringZhejiang University of TechnologyHangzhou China

2. Engineering Research Center of Bioconversion and Biopurification of Ministry of EducationZhejiang University of TechnologyHangzhou China

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bit.27203

Reference50 articles.

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4. Catalysis in the nitrilase superfamily

5. Burns M. P. Weaver J. K. &Wong J. W.(2010).Stereoselective bioconversion of aliphatic dinitriles into cyano carboxylic acids. Patent no. US 7 727 749 B2.

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