Needless electrospun collagen/hyaluronic acid nanofibers for skin moisturization: Research

Abstract

AbstractThis study investigated the potential of electrospun collagen/hyaluronic acid nanofibers for use in biomedicine and skincare. Needleless electrospinning technology employed in the production process resulted in nanofibers with consistent fiber diameters and improved mechanical properties. The composite nanofibers demonstrated impressive tensile strength and elongation capabilities, indicating a favorable interaction between collagen and hyaluronic acid (HA). Cellular assays revealed that the collagen/HA scaffolds facilitated superior cell adhesion and proliferation compared with the control scaffolds, indicating their biocompatibility and potential for tissue engineering. This biomaterial offers an environment‐friendly alternative to conventional skincare products by eliminating the need for preservatives and reducing waste. Although the initial costs are high, the long‐term benefits of material durability and active ingredient efficacy provide compelling cases for industrial adoption. Our findings suggest that collagen/HA nanofibers have the potential to be the next‐generation materials for regenerative medicine and skincare. Further research is required to optimize their production and assess the economic feasibility of skincare and tissue engineering applications.