Extracting functional groups of ALLINI to design derivatives of FDA-approved drugs: Inhibition of HIV-1 integrase-Reference-Cited by-同舟云学术

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Extracting functional groups of ALLINI to design derivatives of FDA-approved drugs: Inhibition of HIV-1 integrase

Published:2018-02-21 Issue:4 Volume:65 Page:594-607
ISSN:0885-4513
Container-title:Biotechnology and Applied Biochemistry
language:en
Short-container-title:Biotechnology and Applied Biochemistry

Author:

Kalathiya Umesh¹^ORCID,Padariya Monikaben¹,Baginski Maciej¹

Affiliation:

1. Department of Pharmaceutical Technology and Biochemistry; Faculty of Chemistry; Gdansk University of Technology; Gdansk Poland

Publisher

Wiley

Subject

Process Chemistry and Technology,Drug Discovery,Applied Microbiology and Biotechnology,Biomedical Engineering,Molecular Medicine,General Medicine,Bioengineering,Biotechnology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/bab.1646/fullpdf

Reference70 articles.

1. Piecing together the structure of retroviral integrase, an important target in AIDS therapy

2. The core and carboxyl-terminal domains of the integrase protein of human immunodeficiency virus type 1 each contribute to nonspecific DNA binding

3. Enhanced and coordinated processing of synapsed viral DNA ends by retroviral integrases in vitro.

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