Multimodal Precision Imaging of Pulmonary Nanoparticle Delivery in Mice: Dynamics of Application, Spatial Distribution, and Dosimetry

Author:

Yang Lin123ORCID,Gradl Regine456ORCID,Dierolf Martin45ORCID,Möller Winfried12,Kutschke David12,Feuchtinger Annette7,Hehn Lorenz48,Donnelley Martin910,Günther Benedikt45,Achterhold Klaus45ORCID,Walch Axel7,Stoeger Tobias12ORCID,Razansky Daniel3111213,Pfeiffer Franz4568,Morgan Kaye S.4614ORCID,Schmid Otmar12ORCID

Affiliation:

1. Comprehensive Pneumology Center (CPC‐M)Member of the German Center for Lung Research (DZL) Munich 81377 Germany

2. Institute of Lung Biology and DiseaseHelmholtz Zentrum München‐German Research Center for Environmental Health Neuherberg 85764 Germany

3. Faculty of MedicineTechnical University of Munich Munich 80333 Germany

4. Chair of Biomedical PhysicsDepartment of PhysicsTechnical University of Munich Garching 85748 Germany

5. Munich School of BioEngineeringTechnical University of Munich Garching 85748 Germany

6. Institute for Advanced StudyTechnical University of Munich Garching 85748 Germany

7. Research Unit Analytical PathologyHelmholtz Zentrum München Neuherberg 85764 Germany

8. Department of Diagnostic and Interventional RadiologyKlinikum rechts der IsarTechnical University of Munich München 81675 Germany

9. Robinson Research Institute and Adelaide Medical SchoolUniversity of Adelaide Adelaide 5000 Australia

10. Respiratory and Sleep MedicineWomen's and Children's Hospital North Adelaide SA 5006 Australia

11. Institute for Biological and Medical Imaging (IBMI)Helmholtz Zentrum München Neuherberg 85764 Germany

12. Faculty of Medicine and Institute of Pharmacology and ToxicologyUniversity of Zurich Zurich CH‐8057 Switzerland

13. Institute for Biomedical Engineering and Department of Information Technology and Electrical EngineeringETH Zurich Zurich 8093 Switzerland

14. School of Physics and AstronomyMonash University Clayton Victoria 3800 Australia

Funder

Horizon 2020

China Scholarship Council

Veski

Seventh Framework Programme

European Commission

National Health and Medical Research Council

Publisher

Wiley

Subject

Biomaterials,Biotechnology,General Materials Science,General Chemistry

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