1. The First Affiliated Hospital, College of Medicine; Zhejiang University; Hangzhou 310003 China
2. Department of Pharmacology; College of Pharmaceutical Sciences, Zhejiang University; Hangzhou 310058 China
3. Center for Biomaterials and Biopathways; Department of Chemistry; Zhejiang University; Hangzhou 310027 China
4. Shanghai Institute of Materia Medica; Chinese Academy of Sciences; Shanghai 201203 China