Bepridil exhibits anti-leukemic activity associated with NOTCH1 pathway inhibition in chronic lymphocytic leukemia

Author:

Baldoni Stefano1,Del Papa Beatrice2,Dorillo Erica2,Aureli Patrizia2,De Falco Filomena2,Rompietti Chiara2,Sorcini Daniele2,Varasano Emanuela2,Cecchini Debora2,Zei Tiziana2,Di Tommaso Ambra1,Rosati Emanuela3,Alexe Gabriela4,Roti Giovanni5,Stegmaier Kimberly4,Di Ianni Mauro67,Falzetti Franca2,Sportoletti Paolo2ORCID

Affiliation:

1. Hematology Section, Department of Life, Health and Environmental Sciences; University of L'Aquila; L'Aquila Italy

2. Institute of Hematology-Centro di Ricerche Emato-Oncologiche (CREO), University of Perugia; Perugia Italy

3. Biosciences and Medical Embryology Section, Department of Experimental Medicine; University of Perugia; Perugia Italy

4. Department of Pediatric Oncology; Dana-Farber Cancer Institute and Boston Children's Hospital, Harvard Medical School; Boston MA

5. Hematology and BMT Unit, Department of Medicine and Surgery; University of Parma; Parma Italy

6. Department of Medicine and Aging Sciences; University of Chieti Pescara; Chieti Italy

7. Department of Hematology; Transfusion Medicine and Biotechnologies, Ospedale Civile; Pescara Italy

Funder

Ministero dell’Istruzione, dell’Università e della Ricerca

Associazione Italiana per la Ricerca sul Cancro

Publisher

Wiley

Subject

Cancer Research,Oncology

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