A physiologically based pharmacokinetic modeling approach to predict drug-drug interactions between domperidone and inhibitors of CYP3A4
Author:
Affiliation:
1. Janssen Research & Development; LLC, Raritan; NJ USA
2. Janssen Research & Development; A Division of Janssen Pharmaceutica NV; Beerse Belgium
Publisher
Wiley
Subject
Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine
Reference21 articles.
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2. Mechanism-based inhibition of human cytochrome P4503A4 by domperidone;Chang;Xenobiotica,2010
3. Absence of QTc prolongation with domperidone: a randomized, double-blind, placebo- and positive-controlled thorough QT/QTc study in healthy volunteers;Biewenga;Clin Pharmacol Drug Dev,2015
4. Mechanistic approaches to volume of distribution predictions: understanding the processes;Rodgers;Pharm Res,2007
5. Prediction of time-dependent CYP3A4 drug-drug interactions by physiologically based pharmacokinetic modelling: impact of inactivation parameters and enzyme turnover;Rowland Yeo;Eur J Pharm Sci,2011
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