Distribution ofMED12mutations in fibroadenomas and phyllodes tumors of the breast-implications for tumor biology and pathological diagnosis

Author:

Pfarr Nicole1,Kriegsmann Mark1,Sinn Peter1,Klauschen Frederick2,Endris Volker1,Herpel Esther13,Muckenhuber Alexander1,Jesinghaus Moritz1,Klosterhalfen Bernd4,Penzel Roland1,Lennerz Jochen K.5,Weichert Wilko16,Stenzinger Albrecht1

Affiliation:

1. Institute of Pathology, University Hospital Heidelberg; Im Neuenheimer Feld 224 69120 Heidelberg Germany

2. Institute of Pathology, Charité University Hospital; Charitéplatz 1 10117 Berlin Germany

3. Tissue Bank of the National Center for Tumor Diseases (NCT); Heidelberg Germay

4. Institute of Pathology, Dueren Hospital; Roonstrasse 30 52351 Dueren Germany

5. Department of Pathology; Massachusetts General Hospital/Harvard Medical School, Center for Integrated Diagnostics (CID); 55 Fruit Street 02114 Boston MA USA

6. Member of the German Cancer Consortium (DKTK) and National Center for Tumor Diseases (NCT); 69120 Heidelberg Germany

Funder

German Cancer Consortium (DKTK)

Publisher

Wiley

Subject

Cancer Research,Genetics

Reference36 articles.

1. Phyllodes tumor of the breast;Belkacémi;Int J Radiat Oncol Biol Phys,2008

2. MED12 and HMGA2 mutations: Two independent genetic events in uterine leiomyoma and leiomyosarcoma;Bertsch;Mod Pathol,2014

3. Long-term risk of breast cancer in women with fibroadenoma;Dupont;N Engl J Med,1994

4. COSMIC: Exploring the world's knowledge of somatic mutations in human cancer;Forbes;Nucleic Acids Res,2014

5. Absence of genetic abnormalities in fibroadenomas of the breast determined at p53 gene mutations and microsatellite alterations;Franco;Cancer Res,2001

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