Affiliation:
1. College of Mechanical Engineering Sichuan University Chengdu China
2. Department of Applied Mechanics Sichuan University Chengdu China
Abstract
AbstractProsthetic polymeric heart valves (PHVs) have the potential to overcome the inherent material and design limitations of traditional valves in the treatment of valvular heart disease; however, their durability remains limited. Optimal design of the valve structure is necessary to improve their durability. This study aimed to enhance the fatigue resistance of PHVs by improving the stress distribution. Iterative subregional thickening of the leaflets was used, and the mechanical stress distribution and hemodynamics of these polymeric tri‐leaflet valves were characterized using a fluid–structure interaction approach. Subregional thickening led to a reduction in stress concentration on the leaflet, with the effective orifice area still meeting ISO 5840‐3 and the regurgitant volume achieving a similar value to those in previous studies. The maximum stress in the final iteration was reduced by 28% compared with that of the prototype. The proposed method shows potential for analyzing the stress distribution and hemodynamic performance of subregional thickened valves and can further improve the durability of PHVs.
Subject
Applied Mathematics,Computational Theory and Mathematics,Molecular Biology,Modeling and Simulation,Biomedical Engineering,Software
Cited by
1 articles.
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