Cancer‐associated fibroblasts potentiate colorectal cancer progression by crosstalk of the IGF2IGF1R and Hippo–YAP1 signaling pathways

Author:

Zhang Jinglin1,Chen Bonan123,Li Hui123,Wang Yifei123,Liu Xiaoli123,Wong Kit Yee123,Chan Wai Nok123,Chan Aden KY1ORCID,Cheung Alvin HK1,Leung Kam Tong4,Dong Yujuan2,Pan Yi5,Ke Huixing6,Liang Li7ORCID,Zhou Zhaocai8,Xiao Jianyong9,Wong Chi Chun2,Wu William KK10ORCID,Cheng Alfred SL11,Ma Brigette BY312,Yu Jun213ORCID,Lo Kwok Wai13ORCID,Kang Wei123ORCID,

Affiliation:

1. Department of Anatomical and Cellular Pathology Prince of Wales Hospital, The Chinese University of Hong Kong Hong Kong SAR PR China

2. Institute of Digestive Disease State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong Hong Kong SAR PR China

3. State Key Laboratory of Translational Oncology Sir Y.K. Pao Cancer Center, The Chinese University of Hong Kong Hong Kong SAR PR China

4. Department of Pediatrics The Chinese University of Hong Kong Hong Kong SAR PR China

5. Department of Pathology, National Cancer Center National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing PR China

6. Department of Respiratory and Critical Care Medicine China National Center of Gerontology, Bejing Hospital Beijing PR China

7. Department of Pathology, Nanfang Hospital and Basic Medical College Southern Medical University, Guangdong Province Key Laboratory of Molecular Tumor Pathology Guangzhou PR China

8. State Key Laboratory of Genetic Engineering, School of Life Sciences Zhongshan Hospital, Fudan University Shanghai PR China

9. Department of Biochemistry, School of Basic Medicine Guangzhou University of Chinese Medicine Guangzhou PR China

10. Department of Anaesthesia and Intensive Care The Chinese University of Hong Kong Hong Kong SAR PR China

11. School of Biomedical Sciences The Chinese University of Hong Kong Hong Kong SAR PR China

12. Department of Clinical Oncology, Hong Kong Cancer Institute The Chinese University of Hong Kong Hong Kong SAR PR China

13. Department of Medicine and Therapeutics The Chinese University of Hong Kong Hong Kong SAR PR China

Funder

National Natural Science Foundation of China

Research Grants Council, University Grants Committee

Publisher

Wiley

Subject

Pathology and Forensic Medicine

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