Antibiotic-mediated bacteriome depletion in Apc Min/+ mice is associated with reduction in mucus-producing goblet cells and increased colorectal cancer progression

Author:

Kaur Kamaljeet1,Saxena Arpit1,Debnath Irina2,O'Brien Jacqueline L.3,Ajami Nadim J.3,Auchtung Thomas A.3,Petrosino Joseph F.3,Sougiannis Alexander-Jacques1,Depaep Sarah1,Chumanevich Alexander1,Gummadidala Phani M.2,Omebeyinje Mayomi H.2,Banerjee Sourav4,Chatzistamou Ioulia5,Chakraborty Paramita6,Fayad Raja17,Berger Franklin G.7,Carson James A.17,Chanda Anindya27ORCID

Affiliation:

1. Exercise Science, Arnold School of Public Health; University of South Carolina; Columbia South Carolina

2. Environmental Health Sciences, Arnold School of Public Health; University of South Carolina; Columbia South Carolina

3. The Alkek Center for Metagenomics and Microbiome Research; Department of Molecular Virology and Microbiology; Baylor College of Medicine; Houston Texas

4. Mechanical Engineering; University of South Carolina; Columbia South Carolina

5. Pathology, Microbiology& Immunology, School of Medicine; University of South Carolina; Columbia South Carolina

6. Department of Statistics; University of South Carolina; Columbia South Carolina

7. Center for Colon Cancer Research; University of South Carolina; Columbia South Carolina

Funder

University of South Carolina

National Institutes of Health

National Cancer Institute

Publisher

Wiley

Subject

Cancer Research,Radiology, Nuclear Medicine and imaging,Oncology

Reference73 articles.

1. Understanding the Gut microbiota in inflammatory and functional gastrointestinal diseases;Sundin;Psychosom. Med.,2017

2. Exploring the human microbiome from multiple perspectives: factors altering its composition and function;Rojo;FEMS Microbiol. Rev.,2017

3. The Gut Microbiome: Connecting Spatial Organization to Function;Tropini;Cell Host Microbe,2017

4. Gut microbiota and probiotics: focus on diabetes mellitus;Bordalo Tonucci;Crit. Rev. Food Sci. Nutr.,2017

5. Microbiota and metabolic syndrome;Altuntas;Turk. Kardiyol. Dern. Ars.,2017

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