The insulin receptor changes conformation in unforeseen ways on ligand binding: Sharpening the picture of insulin receptor activation
Author:
Affiliation:
1. Walter and Eliza Hall Institute of Medical Research; Parkville Victoria Australia
2. Department of Medical Biology; University of Melbourne; Parkville Victoria Australia
Publisher
Wiley
Subject
General Biochemistry, Genetics and Molecular Biology
Reference89 articles.
1. Insulin interactions with its receptors: experimental evidence for negative cooperativity;De Meyts;Biochem Biophys Res Commun,1973
2. The structural basis of insulin and insulin-like growth factor-I receptor binding and negative co-operativity, and its relevance to mitogenic versus metabolic signalling;De Meyts;Diabetologia,1994
3. Harmonic oscillator model of the insulin and IGF1 receptors' allosteric binding and activation;Kiselyov;Molec Sys Biol,2009
4. Insight into the molecular basis for the kinetic differences between the two insulin receptor isoforms;Knudsen;Biochem J,2011
5. How insulin engages its primary binding site on the insulin receptor;Menting;Nature,2013
Cited by 65 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Spontaneous Dimerization and Distinct Packing Modes of Transmembrane Domains in Receptor Tyrosine Kinases;2024-05-13
2. Derivatization with fatty acids in peptide and protein drug discovery;Nature Reviews Drug Discovery;2022-08-24
3. The Insulin Receptor: An Important Target for the Development of Novel Medicines and Pesticides;International Journal of Molecular Sciences;2022-07-14
4. Progress in Simulation Studies of Insulin Structure and Function;Frontiers in Endocrinology;2022-06-20
5. An overview of the insulin signaling pathway in model organisms Drosophila melanogaster and Caenorhabditis elegans;Peptides;2021-11
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3