Identification and characterization ofin vitroandin vivometabolites of steroidal alkaloid veratramine

Author:

Lyu Chunming12,Zhou Wenbin3,Zhang Yufeng2,Zhang Shen4,Kou Fang3,Wei Hai3,Zhang Ning1,Zuo Zhong2

Affiliation:

1. Technology Laboratory Center; Shanghai University of Traditional Chinese Medicine; Shanghai PR China

2. School of Pharmacy, Faculty of Medicine; The Chinese University of Hong Kong, Shatin, New Territories; Hong Kong SAR

3. Center for Chinese Medical Therapy and Systems Biology; Shanghai University of Traditional Chinese Medicine; Shanghai PR China

4. Department of Rehabilitation; Changzheng Hospital Affiliated to Second Military Medicine University; Shanghai 200003 PR China

Funder

Science and Technology Commission of Shanghai Municipality

Ministry of Education of the People's Republic of China

Shanghai Municipal Education Commission

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Reference68 articles.

1. Chemistry, bioactivity and geographical diversity of steroidal alkaloids from the Liliaceae family;Li;Nat Prod Rep,2006

2. Chromatographic analysis of Fritillaria isosteroidal alkaloids, the active ingredients of Beimu, the antitussive traditional Chinese medicinal herb;Lin;J Chromatogr A,2001

3. Hypotensive effect and toxicology of total alkaloids and veratramine from roots and rhizomes of Veratrum nigrum L. in spontaneously hypertensive rats;Wang;Pharmazie,2008

4. Carbon-13 and proton nuclear magnetic resonance spectra of Veratrum alkaloids;Gaffield;J Nat Prod,1986

5. Veratramine, a new alkaloid of white hellebore (Veratrum grandifiorum Loes. fil.);Saito;Bull Chem Soc Jpn,1940

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