Pneumonia due to Achromobacter xylosoxidans with a chronic course resembling non‐tuberculous mycobacterial infection

Author:

Kotani Tomoko1ORCID,Inazaki Toshiaki1,Kasai Hajime1234,Rakuman Shintaro1,Suzuki Kenichi1,Urushibara Takashi1

Affiliation:

1. Department of Respirology Kimitsu Chuo Hospital Kisarazu Japan

2. Department of Respirology Graduate School of Medicine, Chiba University Chiba Japan

3. Department of Medical Education Graduate School of Medicine, Chiba University Chiba Japan

4. Health Professional Development Center Chiba University Hospital Chiba Japan

Abstract

AbstractAchromobacter xylosoxidans is a common bacterium that rarely causes pneumonia. Determining whether A. xylosoxidans is the cause of lung infection in patients suspected of having chronic infectious lung disease is challenging because it can present with colonization. We report a case of a 56‐year‐old immunocompetent woman suspected of having non‐tuberculous mycobacteria (NTM) infection on imaging examination and monitored for 3 years. Sputum examinations revealed A. xylosoxidans several times, and it was determined to be a colonization. A. xylosoxidans was isolated from bronchial lavage fluid and aspirated sputum, but no evidence of NTM was observed. She was diagnosed with A. xylosoxidans infection and given ceftazidime for 2 weeks. Her symptoms and imaging findings improved rapidly after treatment, without recurrences. A. xylosoxidans rarely causes chronic lower respiratory tract infections similar to NTM in immunocompetent patients. A. xylosoxidans may be a target for treatment when detected in lower respiratory tract specimens.

Publisher

Wiley

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