Genus Streptomyces: Recent advances for biotechnological purposes

Author:

de Lima Júnior Apolonio Alves1,de Sousa Ednan Cardoso2,de Oliveira Thales Henrique Barbosa1ORCID,de Santana Raphael Carlos Férrer3,da Silva Silvia Katrine Rabelo4,Coelho Luana Cassandra Breitenbach Barroso1

Affiliation:

1. Departamento de Bioquímica, Centro de Biociências, CB Universidade Federal de Pernambuco (UFPE), Avenida Professor Moraes Rego, S/N, Cidade Universitária Recife Pernambuco Brazil

2. Departamento de Saúde Faculdade Santa Maria Cajazeiras Paraíba Brazil

3. Departamento de Saúde Centro Universitário Maurício de Nassau (UNINASSAU) Recife Pernambuco Brazil

4. Instituto de Saúde Coletiva Universidade Federal do Oeste do Pará Santarém Pará Brazil

Abstract

AbstractActinomycetes are a distinct group of filamentous bacteria. The Streptomyces genus within this group has been extensively studied over the years, with substantial contributions to society and science. This genus is known for its antimicrobial production, as well as antitumor, biopesticide, and immunomodulatory properties. Therefore, the extraordinary plasticity of the Streptomyces genus has inspired new research techniques. The newest way of exploring Streptomyces has comprised the discovery of new natural metabolites and the application of emerging tools such as CRISPR technology in drug discovery. In this narrative review, we explore relevant published literature concerning the ongoing novelties of the Streptomyces genus.

Publisher

Wiley

Subject

Process Chemistry and Technology,Drug Discovery,Applied Microbiology and Biotechnology,Biomedical Engineering,Molecular Medicine,General Medicine,Bioengineering,Biotechnology

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