Structure of a designed tetrahedral protein assembly variant engineered to have improved soluble expression

Author:

Bale Jacob B.12,Park Rachel U.1,Liu Yuxi3,Gonen Shane14,Gonen Tamir4,Cascio Duilio5,King Neil P.16,Yeates Todd O.35,Baker David167

Affiliation:

1. Department of Biochemistry; University of Washington; Seattle Washington 98195

2. Graduate Program in Molecular and Cellular Biology; University of Washington; Seattle Washington 98195

3. Department of Chemistry and Biochemistry; UCLA; Los Angeles California 90095

4. Janelia Research Campus, Howard Hughes Medical Institute; Ashburn Virginia 20147

5. Institute for Genomics and Proteomics, UCLA-DOE; Los Angeles California 90095

6. Institute for Protein Design, University of Washington; Seattle Washington 98195

7. Howard Hughes Medical Institute, University of Washington; Seattle Washington 98195

Funder

National Science Foundation

Defense Advanced Research Projects Agency

Howard Hughes Medical Institute, JFRC visitor program

Publisher

Wiley

Subject

Molecular Biology,Biochemistry

Reference42 articles.

1. Structural symmetry and protein function;Goodsell;Annu Rev Biophys Biomol Struct,2000

2. Protein-protein interaction and quaternary structure;Janin;Q Rev Biophys,2008

3. Principles for designing ordered protein assemblies;Lai;Trends Cell Biol,2012

4. Practical approaches to designing novel protein assemblies;King;Curr Opin Struct Biol,2013

5. Constructing arrays of proteins;Sinclair;Curr Opin Chem Biol,2013

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