Drug therapy targeting pyrophosphate slows the ossification of spinal ligaments in twy mice
Author:
Affiliation:
1. Department of Orthopaedic Surgery; School of Medicine; Hokkaido University; Kita-15 Nishi-7 Kita-ku Sapporo 060-8638 Japan
Publisher
Wiley
Subject
Orthopedics and Sports Medicine
Reference21 articles.
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3. Recent progress in the study of pathogenesis of ossification of the posterior longitudinal ligament;Sakou;J Orthop Sci,2000
4. A genome-wide association study identifies susceptibility loci for ossification of the posterior longitudinal ligament of the spine;Nakajima;Nat genetics,2014
5. Teriparatide improves trabecular osteoporosis but simultaneously promotes ankylosis of the spine in the twy mouse model for diffuse idiopathic skeletal hyperostosis;Hamano;Calcif Tissue Int,2016
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1. Enpp1 mutations promote upregulation of hedgehog signaling in heterotopic ossification with aging;Journal of Bone and Mineral Metabolism;2024-08-30
2. Effect of mechanical stimulation on tissue heterotopic ossification: an in vivo experimental study;Frontiers in Physiology;2023-10-11
3. New Evaluation Methods with High Sensitivity for Motor Function of the Ossification of the Posterior Longitudinal Ligament in ttw/ttw Mouse Model;Neurochemical Journal;2022-06
4. Cyclic Tensile Stress to Rat Thoracolumbar Ligamentum Flavum Inducing the Ossification of Ligamentum Flavum;Spine;2021-05-04
5. Extracellular pyrophosphate: The body's “water softener”;Bone;2020-05
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