Enantioselective disposition of (R)-salmeterol and (S)-salmeterol in urine following inhaled dosing and application to doping control

Author:

Jacobson Glenn A.1,Hostrup Morten23,Narkowicz Christian K.1,Nichols David S.4,Haydn Walters E.1

Affiliation:

1. School of Medicine; University of Tasmania; Hobart Australia

2. Section of Integrative Physiology, Department of Nutrition Exercise and Sports; University of Copenhagen; Denmark

3. Department of Respiratory Medicine; Bispebjerg University Hospital; Denmark

4. Central Science Laboratory; University of Tasmania; Hobart Australia

Funder

Division of Pharmacy, School of Medicine, University of Tasmania

Publisher

Wiley

Subject

Spectroscopy,Pharmaceutical Science,Environmental Chemistry,Analytical Chemistry

Reference19 articles.

1. The beta-adrenoceptor pharmacology of the enantiomers of salmeterol;Nials;Am. Rev. Respir. Dis.,1994

2. Beta2-agonist doping control and optical isomer challenges;Jacobson;Sports Med.,2016

3. Hostrup M Bangsbo J Active voice: inhaled Beta2-agonist - a performance-enhancing agent? Sports Medicine Bulletin 2016 http://www.multibriefs.com/briefs/acsm/active022316.htm

4. World Anti-Doping Agency (WADA). Prohibited List 2016. World Anti-Doping Code International Standard 2016 https://wada-main-prod.s3.amazonaws.com/resources/files/wada-2016-prohibited-list-en.pdf

5. Martindale Martindale: The Complete Drug Reference 2016 https://www.medicinescomplete.com/mc/martindale/current/

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