The mGluR5 negative allosteric modulator dipraglurant reduces dyskinesia in the MPTP macaque model-Reference-Cited by-同舟云学术

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The mGluR5 negative allosteric modulator dipraglurant reduces dyskinesia in the MPTP macaque model

Published:2014-05-27 Issue:8 Volume:29 Page:1074-1079
ISSN:0885-3185
Container-title:Movement Disorders
language:en
Short-container-title:Mov Disord.

Author:

Bezard Erwan¹²³⁴⁵,Pioli Elsa Y.¹,Li Qin¹⁵,Girard Françoise⁶,Mutel Vincent⁶,Keywood Charlotte⁶,Tison Francois²³⁴,Rascol Olivier⁷⁸⁹,Poli Sonia M.⁶

Affiliation:

1. Motac neuroscience; Manchester UK

2. Université de Bordeaux; Institut des Maladies Neurodégénératives, UMR 5293; Bordeaux France

3. CNRS; Institut des Maladies Neurodégénératives, UMR 5293; Bordeaux France

4. Service de Neurologie; CHU de Bordeaux; Pessac France

5. Institute of Laboratory Animal Sciences; China Academy of Medical Sciences; Beijing China

6. Addex Pharma SA; Plan Les Ouates; Switzerland

7. CIC Toulouse; France

8. Départements de Pharmacologie Clinique et Neurosciences; INSERM CIC9302; CHU de Toulouse France

9. Service de Pharmacologie; Faculté de Médecine, CHU de Toulouse, Université de Toulouse; France

Publisher

Wiley

Subject

Neurology (clinical),Neurology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/mds.25920/fullpdf

Reference29 articles.

1. A five-year study of the incidence of dyskinesia in patients with early Parkinson's disease who were treated with ropinirole or levodopa;Rascol;N Engl J Med,2000

2. Effects of dyskinesias in Parkinson's disease on quality of life and health-related costs: a prospective European study;Pechevis;Eur J Neurol,2005

3. A mGluR5 antagonist under clinical development improves L-DOPA-induced dyskinesia in parkinsonian rats and monkeys;Rylander;Neurobiol Dis,2010

4. Effects of group I metabotropic glutamate receptors blockade in experimental models of Parkinson's disease;Dekundy;Brain Res Bull,2006

5. Systemic administration of an mGluR5 antagonist, but not unilateral subthalamic lesion, counteracts l-DOPA-induced dyskinesias in a rodent model of Parkinson's disease;Levandis;Neurobiol Dis,2008

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2. Positive allosteric mGluR2 modulation with BINA alleviates dyskinesia and psychosis-like behaviours in the MPTP-lesioned marmoset;Naunyn-Schmiedeberg's Archives of Pharmacology;2024-06-11

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4. Suppression of presynaptic corticostriatal glutamate activity attenuates L-dopa-induced dyskinesia in 6-OHDA-lesioned Parkinson's disease mice;Neurobiology of Disease;2024-04

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