Inhibition of ACLY Leads to Suppression of Osteoclast Differentiation and Function Via Regulation of Histone Acetylation
Author:
Affiliation:
1. Department of Orthopedic Surgery and Biological Engineering and Regenerative Medicine Center, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China
Publisher
Wiley
Subject
Orthopedics and Sports Medicine,Endocrinology, Diabetes and Metabolism
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/jbmr.4399
Reference47 articles.
1. Bone Remodeling: Histone Modifications as Fate Determinants of Bone Cell Differentiation
2. Epigenetic regulation of osteoclast differentiation: Possible involvement of Jmjd3 in the histone demethylation of Nfatc1
3. EZH2 Supports Osteoclast Differentiation and Bone Resorption Via Epigenetic and Cytoplasmic Targets
4. Histone deacetylases 1 and 2 inhibition suppresses cytokine production and osteoclast bone resorption in vitro
5. DNMT and HDAC inhibitors modulate MMP-9-dependent H3 N-terminal tail proteolysis and osteoclastogenesis
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