A modular engineering strategy for high‐level production of protopanaxadiol from ethanol by Saccharomyces cerevisiae

Author:

Zhao Fanglong1,Bai Peng1,Nan Weihua1,Li Dashuai1,Zhang Chuanbo1,Lu Chunzhe1ORCID,Qi Haishan1,Lu Wenyu123

Affiliation:

1. Dept. of Biological EngineeringSchool of Chemical Engineering and Technology, Tianjin University Tianjin P.R. China

2. Key Laboratory of System BioengineeringTianjin University, Ministry of Education Tianjin P.R. China

3. Collaborative Innovation Center of Chemical Science and EngineeringTianjin University, SynBio Res Platform Tianjin P.R. China

Funder

National Basic Research Program of China

Publisher

Wiley

Subject

General Chemical Engineering,Environmental Engineering,Biotechnology

Reference37 articles.

1. Ginsenoside 20(S)‐protopanaxadiol suppresses viability of human glioblastoma cells via down‐regulation of cell adhesion proteins and cell‐cycle arrest;Wanderi C;Anticancer Res,2008

2. Protopanaxadiol, an Active Ginseng Metabolite, Significantly Enhances the Effects of Fluorouracil on Colon Cancer

3. HuiYZ ZirongY ZhiqiY QiangY.Use of 20(S)‐Protopanaxadiol in Manufacture of Antidepressants. 2009. US8148354 B2.

4. The preparation method of 20(S)‐protopanaxadiol and 20(S)‐protopanaxatriol;Liang G;J Beijing Normal Univ,2011

5. Enzymatic preparation of 20(S, R)-protopanaxadiol by transformation of 20(S, R)-Rg3 from black ginseng

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