Cell-controlled hybrid perfusion fed-batch CHO cell process provides significant productivity improvement over conventional fed-batch cultures
Author:
Affiliation:
1. Pfizer, Inc.; 1 Burtt Road Andover Massachusetts 01810
Publisher
Wiley
Subject
Applied Microbiology and Biotechnology,Bioengineering,Biotechnology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/bit.26259/fullpdf
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3. Very high density of CHO cells in perfusion by ATF or TFF in WAVE bioreactor. Part I. Effect of the cell density on the process;Clincke;Biotechnol Prog,2013
4. Use of cell bleed in a high cell density perfusion culture and multivariable control of biomass and metabolite concentrations;Deschênes;Asia-Pacific Jrnl of Chem Eng,2006
5. Chromatographic analysis of the acidic and basic species of recombinant monoclonal antibodies;Du;MAbs,2012
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