A silicon‐labelled amino acid suitable for late‐stage fluorination and unexpected oxidative cleavage reactions in the preparation of a key intermediate in the Strecker synthesis-Reference-Cited by-同舟云学术

A silicon‐labelled amino acid suitable for late‐stage fluorination and unexpected oxidative cleavage reactions in the preparation of a key intermediate in the Strecker synthesis

Published:2018-04-20 Issue:3 Volume:110 Page:
ISSN:2475-8817
Container-title:Peptide Science
language:en
Short-container-title:Peptide Science

Author:

Scroggie Kymberley R.¹,Alcock Lisa J.¹,Matos Maria J.²,Bernardes Gonçalo J. L.²³,Perkins Michael V.¹,Chalker Justin M.¹^ORCID

Affiliation:

1. Flinders University, College of Science and EngineeringSouth Australia5042 Australia

2. Department of ChemistryUniversity of CambridgeCambridgeCB2 1EW United Kingdom

3. Faculdade de Medicina, Universidade de Lisboa, Avenida Professor Egas MonizInstituto de Medicina MolecularLisboa1649‐028 Portugal

Funder

Australian Research Council

European Research Council

Publisher

Wiley

Subject

Organic Chemistry,Biomaterials,Biochemistry,Biophysics

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/pep2.24069

Reference43 articles.

1. Target-specific delivery of peptide-based probes for PET imaging

2. From Unorthodox to Established: The Current Status of 18F-Trifluoroborate- and 18F-SiFA-Based Radiopharmaceuticals in PET Nuclear Imaging

3. Synthesis, Radiolabeling, and Biological Evaluation of (R)- and (S)-2-Amino-5-[18F]fluoro-2-methylpentanoic Acid ((R)-, (S)-[18F]FAMPe) as Potential Positron Emission Tomography Tracers for Brain Tumors

4. Expedient Synthesis of Fmoc-(S)-γ-Fluoroleucine and Late-Stage Fluorination of Peptides

5. Late-Stage Fluorination: From Fundamentals to Application

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