Stereoregular polyamides with optically‐pure aspartame‐type diketopiperazine derivatives

Author:

Takada Kenji12ORCID,Yin Hongrong2ORCID,Kaneko Tatsuo23ORCID

Affiliation:

1. Department of Organic Material Science Graduate School of Organic Materials Science, Yamagata University Yamagata Japan

2. Energy and Environment Area, Japan Advanced Institute of Science and Technology Nomi Ishikawa Japan

3. Key Laboratory of Synthetic and Biological Colloids School of Chemical and Material Engineering, Jiangnan University Wuxi Jiangsu China

Abstract

AbstractPolyamides (PAs) with aspartame‐derived diketopiperazine (DKP) form specific particles and exhibit high heat resistance. In this study, we investigated the stereostructures of aspartic acid and phenylalanine, which constitute aspartame DKP. Diketopiperazines with different stereostructures were synthesized from D‐ and L‐aspartic acid and D‐ and L‐phenylalanine, and LL‐, DD‐, and LD‐type aminodiketopiperazines (LL, DD, and LD‐ADKPs) were obtained. These ADKPs differed in their crystal forms depending on their stereoisomeric structures. Furthermore, PAs were formed from these ADKPs via polycondensation using triphenyl phosphite/pyridine, and their heat resistance was approximately 300 °C. The secondary structure of each PA was evaluated by circular dichroism, which suggested that LD‐type PAs had a mixed secondary structure of coils and helical structures, unlike the LL and DD types. Precipitated LL, DD, and LLcoDD PAs formed similar particles, whereas the particles of the large LD‐type PA had different particle shapes owing to their different conformations.

Funder

Advanced Low Carbon Technology Research and Development Program

Publisher

Wiley

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