Clustering psychopathology in male anabolic–androgenic steroid users and nonusing weightlifters

Author:

Jørstad Marie Lindvik1ORCID,Scarth Morgan23,Torgersen Svenn3,Pope Harrison Graham45,Bjørnebekk Astrid2

Affiliation:

1. Anabolic Androgenic Steroid Research Group, National Advisory Unit on SUD Treatment, Division of Mental Health and Addiction Oslo University Hospital Oslo Norway

2. Anabolic Androgenic Steroid Research Group, Section for Clinical Addiction Research, Division of Mental Health and Addiction Oslo University Hospital Oslo Norway

3. Department of Psychology University of Oslo Oslo Norway

4. Biological Psychiatry Laboratory McLean Hospital Belmont Massachusetts USA

5. Harvard Medical School, Department of Psychiatry Boston Massachusetts USA

Abstract

AbstractIntroductionPrior research has demonstrated that personality disorders and clinical psychiatric syndromes are common among users of anabolic–androgenic steroids (AAS). However, the prevalence, expression, and severity of psychopathology differ among AAS users and remain poorly understood. In this study, we examine the existence of potential clinically coherent psychopathology subgroups, using cluster procedures.MethodsA sample of 118 male AAS users and 97 weightlifting nonusers was assessed using the Millon Clinical Multiaxial Inventory‐III (MCMI‐III), measuring personality disorders and clinical syndromes. Group differences in MCMI‐III scales were assessed using Wilcoxon‐Mann–Whitney tests and Fisher's exact test. Agglomerative hierarchical clustering was used to identify clusters based on MCMI‐III scale scores from the whole sample.ResultsAAS users displayed significantly higher scores on all personality disorder (except narcissistic) and clinical syndrome scales compared to nonusing weightlifters. The clustering analysis found four separate clusters with different levels and patterns of psychopathology. The “no psychopathology” cluster was most common among nonusing weightlifters, while the three other clusters were more common among AAS users: “severe multipathology,” “low multipathology,” and “mild externalizing.” The “severe multipathology” cluster was found almost exclusively among AAS users. AAS users also displayed the highest scores on drug and alcohol dependence syndromes.ConclusionsAAS users in our sample demonstrated greater psychopathology than the nonusing weightlifters, with many exhibiting multipathology. This may pose a significant challenge to clinical care for AAS users, particularly as there appears to be significant variation in psychopathology in this population. Individual psychiatric profiles should be taken into consideration when providing treatment to this group.Significant Outcomes As a group, AAS users displayed markedly greater psychopathology than nonusing weightlifters. Multipathology was common among AAS users. Four different subgroups of personality profiles were identified with distinct patterns of pathology and severity. Limitations The cross‐sectional nature of the study precludes inferences about causality. The study is limited by possible selection bias, as participants choosing to be involved in research may not be entirely representative for the group as a whole. The study is vulnerable to information bias, as the results are based on self‐report measures and interviews.

Publisher

Wiley

Subject

Behavioral Neuroscience

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