Transient inhibition of CDK2 activity prevents oocyte meiosis I completion and egg activation in mouse-Reference-Cited by-同舟云学术

Transient inhibition of CDK2 activity prevents oocyte meiosis I completion and egg activation in mouse

Published:2022-09-26 Issue:11 Volume:237 Page:4317-4325
ISSN:0021-9541
Container-title:Journal of Cellular Physiology
language:en
Short-container-title:Journal Cellular Physiology

Author:

Li Jian¹^ORCID,Chang Hao‐Ya¹,Yi Zi‐Yun¹^ORCID,Zhang Chun‐Hui¹,Sun Qing‐Yuan²^ORCID,Qian Wei‐Ping¹³

Affiliation:

1. Department of Reproductive Medicine Peking University Shenzhen Hospital Shenzhen Guangdong China

2. Fertility Preservation Lab, Reproductive Medicine Center, Guangdong Second Provincial General Hospital Guangzhou China

3. Guangdong and Shenzhen Key Laboratory of Reproductive Medicine and Genetics, The Center of Reproductive Medicine, Peking University Shenzhen Hospital Shenzhen China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Physiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcp.30885

Reference28 articles.

1. The regulation of maturation promoting factor during prophase I arrest and meiotic entry in mammalian oocytes

2. Cdk1, but not Cdk2, is the sole Cdk that is essential and sufficient to drive resumption of meiosis in mouse oocytes

3. Cdc2–cyclin E complexes regulate the G1/S phase transition

4. Type II Inhibitors Targeting CDK2

5. Cdk2 Knockout Mice Are Viable

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