Bortezomib sensitizes human osteosarcoma cells to adriamycin-induced apoptosis through ROS-dependent activation of p-eIF2α/ATF4/CHOP axis-Reference-Cited by-同舟云学术

Bortezomib sensitizes human osteosarcoma cells to adriamycin-induced apoptosis through ROS-dependent activation of p-eIF2α/ATF4/CHOP axis

Author:

Xian Miao¹,Cao Handi¹,Cao Ji¹,Shao Xuejing¹,Zhu Difeng¹²,Zhang Ning³,Huang Ping⁴,Li Weixu³,Yang Bo¹,Ying Meidan¹^ORCID,He Qiaojun¹

Affiliation:

1. Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences; Zhejiang University; Hangzhou 310058 China

2. Center for Drug Safety Evaluation and Research of Zhejiang University, Zhejiang University; Hangzhou 310058 China

3. Department of Orthopedics; The Second Affiliated Hospital of Zhejiang University, Zhejiang University; Hangzhou 310009 China

4. Department of Pharmacy; Zhejiang Cancer Hospital; Hangzhou 310000 China

Funder

International Science & Technology Cooperation Program of China

Zhejiang Provincial Program for the cultivation of High-level Innovative Health Talents

Zhejiang Provincial Natural Science Foundation of China

Joint Scientific Research Foundation of Ministry of Health and the Health Bureau of Zhejiang Province

National Natural Science Foundation of China

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference48 articles.

4. Synergistic antitumor efficacy by combining adriamycin with recombinant human endostatin in an osteosarcoma model;Xu;Oncol Lett,2011

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