Crystallographic analysis and structure-guided engineering of NADPH-dependentRalstoniasp. Alcohol dehydrogenase toward NADH cosubstrate specificity-Reference-Cited by-同舟云学术

Crystallographic analysis and structure-guided engineering of NADPH-dependentRalstoniasp. Alcohol dehydrogenase toward NADH cosubstrate specificity

Published:2013-07-01 Issue:11 Volume:110 Page:2803-2814
ISSN:0006-3592
Container-title:Biotechnology and Bioengineering
language:en
Short-container-title:Biotechnol. Bioeng.

Author:

Lerchner Alexandra¹,Jarasch Alexander¹,Meining Winfried¹,Schiefner André¹,Skerra Arne¹

Affiliation:

1. Munich Center for Integrated Protein Science, CIPS-M, and Lehrstuhl für Biologische Chemie, Technische Universität München; 85350 Freising-Weihenstephan Germany

Funder

Bundesministerium für Bildung und Forschung, Germany

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Reference52 articles.

1. The catalytic reaction and inhibition mechanism of Drosophila alcohol dehydrogenase: Observation of an enzyme-bound NAD-ketone adduct at 1.4 Å resolution by X-ray crystallography;Benach;J Mol Biol,1999

2. New trends in the recycling of NAD(P)H for the design of sustainable asymmetric reductions catalyzed by dehydrogenases;Berenguer-Murcia;Curr Org Chem,2010

3. The MPI Bioinformatics Toolkit for protein sequence analysis;Biegert;Nucleic Acids Res,2006

4. ALINE: A WYSIWYG protein-sequence alignment editor for publication-quality alignments;Bond;Acta Crystallogr D Biol Crystallogr,2009

5. A highly active decarboxylating dehydrogenase with rationally inverted coenzyme specificity;Chen;Proc Natl Acad Sci USA,1995

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