Quantitative determination of intracellular Asulacrine in MCF-7 breast cancer cells by liquid chromatography-mass spectrometry and its application to cellular pharmacokinetic studies of P188 modified liposomes

Author:

Zang Xiaojie1,Zhang Jingwei1,Zhou Yaqian1,Chen Qianying1,Peng Ying1,Sun Jianguo1,Liu Jiali1,Liu Wenyue1,Wang Guangji1,Zhou Fang1

Affiliation:

1. Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines; China Pharmaceutical University; Nanjing 210009 China

Funder

Jiangsu Province Nature Science Foundation

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference23 articles.

1. Novel steroid carbamates reverse multidrug-resistance in cancer therapy and show linkage among efficacy, loci of drug action and P-glycoprotein's cellular localization;Argov;European Journal of Pharmaceutical Sciences,2010

2. Synthesis, antitumor activity, and DNA binding properties of a new derivative of amsacrine, N-5-dimethyl-9-[(2-methoxy-4-methylsulfonylamino) phenylamino]-4-acridinecarboxamide;Baguley;Cancer Research,1984

3. Potential antitumor agents. 16.4′-(Acridin-9-ylamino)methanesulfonanilides;Cain;Journal of Medicine Chemistry,1975

4. High-performance liquid chromatographic methods for the determination of topoisomerase II inhibitors;Chen;Journal of Chromatography B: Biomedical Science Applications,2001

5. Topoisomerase II-mediated DNA damage produced by 4′-(9-acridinylamino)methanesulfon-m-anisidide and related acridines in L1210 cells and isolated nuclei: relation to cytotoxicity;Covey;Cancer Research,1988

Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3