Nasopharyngeal cancer mortality in disaggregated Asian and non‐Asian Americans

Author:

Hung George A.123ORCID,Vohra Sanah145,Kim Gina16,Jamal Armaan17,Srinivasan Malathi18,Huang Robert J.19,Kim Gloria110,Palaniappan Latha110,Colevas A. Dimitrios111

Affiliation:

1. Stanford Center for Asian Health Research and Education Stanford University School of Medicine Stanford California USA

2. Rutgers Robert Wood Johnson Medical School Piscataway New Jersey USA

3. Rice University Houston Texas USA

4. David Geffen School of Medicine University of California Los Angeles California USA

5. Lineberger Comprehensive Cancer Center University of North Carolina Chapel Hill North Carolina USA

6. Johns Hopkins University Baltimore Maryland USA

7. Department of Medicine Johns Hopkins University School of Medicine Baltimore Maryland USA

8. Division of Primary Care and Population Health Stanford University School of Medicine Stanford California USA

9. Division of Gastroenterology and Hepatology Stanford University School of Medicine Stanford California USA

10. Division of Cardiovascular Medicine Stanford University School of Medicine Stanford California USA

11. Division of Medical Oncology Stanford University School of Medicine Stanford California USA

Abstract

AbstractBackgroundNasopharyngeal carcinoma (NPC) mortality varies based on multiple risk factors. While NPC mortality is higher in Asia, little is known about Asian subgroups in the United States (US).MethodsUsing the 2005–2020 National Vital Statistics System, we examined NPC mortality by age, race (non‐Hispanic black, Hispanic white (HW), non‐Hispanic white (NHW), Chinese, Filipino, Asian Indian, Japanese, Korean, Vietnamese), sex, and nativity (Untied States or foreign‐born).ResultsUpon disaggregation, Chinese (1.96 [CI: 1.78–2.16]), Filipino (0.68 [0.68–1.11]), and Vietnamese Americans (0.68 [0.52–1.10]) had the top age‐adjusted mortality rates (AAMR per 100 000 person‐years). Foreign‐born Chinese, Vietnamese, Filipinos, Asian Indians, and NHW had higher AAMRs compared to US‐born persons. All male groups had higher AAMR compared to females. Stratifying for race, nativity, and sex, foreign‐born Chinese males (4.09 [3.79–4.40]) had the highest AAMR.ConclusionThese findings demonstrate the importance of disaggregating NPC mortality data by Asian subgroups, providing valuable insights for targeted public health interventions in the United States.

Publisher

Wiley

Reference32 articles.

1. Epidemiology and inequality in the incidence and mortality of nasopharynx cancer in Asia;Mahdavifar N;Osong Public Health Res Perspect,2016

2. Nasopharyngeal cancer survival rates: American Cancer Society [Internet]. [cited 2023 Nov 28].https://www.cancer.org/cancer/types/nasopharyngeal‐cancer/detection‐diagnosis‐staging/survival‐rates.html

3. Nasopharyngeal carcinoma (NPC) risk factors: a systematic review and meta‐analysis of the association with lifestyle, diets, socioeconomic and sociodemographic in Asian region;Okekpa SI;Asian Pac J Cancer Prev,2019

4. Nasopharyngeal carcinoma;Chen YP;Lancet,2019

5. Etiological factors of nasopharyngeal carcinoma;Tsao SW;Oral Oncol,2014

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