Engineering an Artificial T‐Cell Stimulating Matrix for Immunotherapy-Reference-Cited by-同舟云学术

Engineering an Artificial T‐Cell Stimulating Matrix for Immunotherapy

Published:2019-04-10 Issue:23 Volume:31 Page:1807359
ISSN:0935-9648
Container-title:Advanced Materials
language:en
Short-container-title:Adv. Mater.

Author:

Hickey John W.¹²³⁴⁵,Dong Yi⁶,Chung Jae Wook⁷,Salathe Sebastian F.⁸,Pruitt Hawley C.⁵⁷,Li Xiaowei⁴⁹,Chang Calvin¹⁴,Fraser Andrew K.¹¹⁰,Bessell Catherine A.⁶,Ewald Andrew J.¹¹⁰¹¹,Gerecht Sharon¹⁵⁷⁹¹²,Mao Hai‐Quan¹⁴⁵⁹,Schneck Jonathan P.²³¹³^ORCID

Affiliation:

1. Department of Biomedical Engineering School of Medicine Baltimore MD 21218 USA

2. Institute for Cell Engineering School of Medicine Baltimore MD 21205 USA

3. Department of Pathology School of Medicine Baltimore MD 21287 USA

4. Translational Tissue Engineering Center Baltimore MD 21287 USA

5. Institute for NanoBioTechnology Baltimore MD 21218 USA

6. Graduate Program in Immunology School of Medicine Baltimore MD 21205 USA

7. Department of Chemical and Biomolecular Engineering Whiting School of Engineering Baltimore MD 21218 USA

8. Department of Biology Krieger School of Arts and Sciences Baltimore MD 21218 USA

9. Department of Materials Science and Engineering Whiting School of Engineering Baltimore MD 21218 USA

10. Department of Cell Biology and Center for Cell Dynamics School of Medicine Baltimore MD 21205 USA

11. Department of Oncology School of Medicine Baltimore MD 21205 USA

12. Physical Sciences‐Oncology Center Baltimore MD 21218 USA

13. Department of Medicine School of Medicine Johns Hopkins University Baltimore MD 21205 USA

Funder

National Science Foundation

Achievement Rewards for College Scientists Foundation

National Institutes of Health

National Institute of General Medical Sciences

National Cancer Institute

Publisher

Wiley

Subject

Mechanical Engineering,Mechanics of Materials,General Materials Science

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/adma.201807359

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2. Tumor antigen–specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired

3. Tetramer guided, cell sorter assisted production of clinical grade autologous NY-ESO-1 specific CD8+ T cells

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