1. Department of Radiology; Shanghai Jiao Tong University Affiliated Sixth People's Hospital; No. 600, Yishan Road Shanghai 200233 P. R. China
2. Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases; Shanghai Institute of Traumatology and Orthopaedics; Ruijin Hospital; Shanghai Jiao Tong University School of Medicine; 197 Ruijin 2nd Road Shanghai 200025 P. R. China
3. Department of Pharmaceutical Sciences Laboratory; Åbo Akademi University; Turku FI-20520 Finland
4. Turku Center for Biotechnology; University of Turku and Åbo Akademi University; Turku FI-20520 Finland
5. Harvard John A. Paulson School of Engineering and Applied Sciences; Harvard University; Cambridge MA 02138 USA
6. Drug Research Program; Division of Pharmaceutical Chemistry and Technology; Faculty of Pharmacy; University of Helsinki; FI-00014 Helsinki Finland
7. Helsinki Institute of Life Science; University of Helsinki; FI-00014 Helsinki Finland