Tamoxifen is a candidate first‐in‐class inhibitor of acid ceramidase that reduces amitotic division in polyploid giant cancer cells—Unrecognized players in tumorigenesis-Reference-Cited by-同舟云学术

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Tamoxifen is a candidate first‐in‐class inhibitor of acid ceramidase that reduces amitotic division in polyploid giant cancer cells—Unrecognized players in tumorigenesis

Published:2020-03-05 Issue:9 Volume:9 Page:3142-3152
ISSN:2045-7634
Container-title:Cancer Medicine
language:en
Short-container-title:Cancer Med

Author:

White‐Gilbertson Shai¹,Lu Ping¹,Jones Christian M.²,Chiodini Stephanie³,Hurley Deborah³,Das Arabinda⁴,Delaney Joe R.²,Norris James S.¹,Voelkel‐Johnson Christina¹²^ORCID

Affiliation:

1. Department of Microbiology & Immunology Medical University of South Carolina Charleston SC USA

2. Department of Biochemistry and Molecular Biology Medical University of South Carolina Charleston SC USA

3. South Carolina Central Cancer RegistrySCDHEC Columbia SC USA

4. Department of Neuroscience Medical University of South Carolina Charleston SC USA

Funder

National Cancer Institute

Medical University of South Carolina

Publisher

Wiley

Subject

Cancer Research,Radiology Nuclear Medicine and imaging,Oncology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cam4.2960

Reference33 articles.

1. Acid ceramidase and its inhibitors: a de novo drug target and a new class of drugs for killing glioblastoma cancer stem cells with high efficiency

2. Complete Acid Ceramidase ablation prevents cancer-initiating cell formation in melanoma cells

3. Radiation-induced acid ceramidase confers prostate cancer resistance and tumor relapse

4. Construction of Conditional Acid Ceramidase Knockout Mice andin vivoEffects on Oocyte Development and Fertility

5. Acid ceramidase is a novel factor required for early embryo survival

Cited by 41 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Amitotic Cell Division, Malignancy, and Resistance to Anticancer Agents: A Tribute to Drs. Walen and Rajaraman;Cancers;2024-09-08

2. Polyploid giant cancer cells: origin, possible pathways of formation, characteristics, and mechanisms of regulation;Frontiers in Cell and Developmental Biology;2024-07-11

3. Surviving the Storm: The Role of Poly‐ and Depolyploidization in Tissues and Tumors;Advanced Science;2024-04-17

4. Transcriptome analysis of polyploid giant cancer cells and their progeny reveals a functional role for p21 in polyploidization and depolyploidization;Journal of Biological Chemistry;2024-04

5. Dormant cancer cells and polyploid giant cancer cells: The roots of cancer recurrence and metastasis;Clinical and Translational Medicine;2024-02

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