Reducing Timp3 or vitronectin ameliorates disease manifestations in CADASIL mice

Author:

Capone Carmen12,Cognat Emmanuel12,Ghezali Lamia12,Baron-Menguy Céline12,Aubin Déborah12,Mesnard Laurent34,Stöhr Heidi5,Domenga-Denier Valérie12,Nelson Mark T.67,Joutel Anne12

Affiliation:

1. Genetics and Pathogenesis of Cerebrovascular Diseases; Inserm, U1161 and Univ Paris Diderot, Sorbonne Paris Cité, UMRS 1161, F-75010; Paris France

2. DHU NeuroVasc, Sorbonne Paris Cité; Paris France

3. Rare and Common Kidney Diseases, Matrix Remodeling and Tissue Repair; Inserm U1155 and Pierre and Marie Curie University, Sorbonne Universities UMR-S 1155, F-75020; Paris France

4. Department of Emergency Nephrological and Renal Transplantation; Tenon Hospital, AP-HP, F-75020; Paris France

5. Institute of Human Genetics; University of Regensburg; Regensburg Germany

6. Department of Pharmacology, College of Medicine; University of Vermont; Burlington VT

7. Institute of Cardiovascular Sciences; University of Manchester; Manchester United Kingdom

Funder

National Research Agency, France

NIH

Totman Medical Research Trust

Leducq Foundation

National Institute of Health and Medical Research

Publisher

Wiley

Subject

Neurology (clinical),Neurology

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