Whole‐exome rare‐variant analysis of Alzheimer's disease and related biomarker traits

Author:

Küçükali Fahri12,Neumann Alexander12,Van Dongen Jasper12,De Pooter Tim23,Joris Geert23,De Rijk Peter23,Ohlei Olena4,Dobricic Valerija4,Bos Isabelle5,Vos Stephanie J. B.6,Engelborghs Sebastiaan27,De Roeck Ellen28,Vandenberghe Rik910,Gabel Silvy910,Meersmans Karen910,Tsolaki Magda11,Verhey Frans61213,Martinez‐Lage Pablo14,Tainta Mikel14,Frisoni Giovanni1516,Blin Oliver17,Richardson Jill C18,Bordet Régis19,Scheltens Philip20,Popp Julius2122,Peyratout Gwendoline23,Johannsen Peter24,Frölich Lutz25,Freund‐Levi Yvonne262728,Streffer Johannes2,Lovestone Simon2930,Legido‐Quigley Cristina3132,Kate Mara ten2033,Barkhof Frederik3334,Zetterberg Henrik3536373839,Bertram Lars440,Strazisar Mojca23,Visser Pieter Jelle620,Van Broeckhoven Christine241,Sleegers Kristel12, ,

Affiliation:

1. Complex Genetics of Alzheimer's Disease Group VIB Center for Molecular Neurology VIB Antwerp Belgium

2. Department of Biomedical Sciences University of Antwerp Antwerp Belgium

3. Neuromics Support Facility VIB Center for Molecular Neurology VIB Antwerp Belgium

4. Lübeck Interdisciplinary Platform for Genome Analytics (LIGA) University of Lübeck Lübeck Germany

5. Netherlands Institute for Health Services Research Utrecht Netherlands

6. Alzheimer Centrum Limburg Maastricht University Maastricht Netherlands

7. Department of Neurology and Brussels Integrated Center for Brain and Memory (Bru‐BRAIN) Universitair Ziekenhuis Brussel (UZ Brussel) and Center for Neurosciences (C4N) Vrije Universiteit Brussel (VUB) Brussels Belgium

8. Department of Neurology and Memory Clinic Hospital Network Antwerp (ZNA) Middelheim and Hoge Beuken Antwerp Belgium

9. University Hospital Leuven Leuven Belgium

10. Department of Neurosciences Laboratory for Cognitive Neurology KU Leuven Leuven Belgium

11. 1st Department of Neurology School of Medicine Faculty of Health Sciences Aristotle University of Thessaloniki Makedonia Thessaloniki Greece

12. Department of Psychiatry and Neuropsychology Maastricht University Maastricht Netherlands

13. School for Mental Health and Neuroscience Maastricht University Maastricht Netherlands

14. Center for Research and Advanced Therapies CITA‐Alzheimer Foundation San Sebastian Spain

15. Department of Psychiatry Faculty of Medicine Geneva University Hospitals Geneva Switzerland

16. RCCS Instituto Centro San Giovanni di Dio Fatebenefratelli Brescia Italy

17. Clinical Pharmacology & Pharmacovigilance Department Marseille University Hospital Marseille France

18. Neurosciences Therapeutic Area GlaxoSmithKline R&D Stevanage United Kingdom

19. Neuroscience & Cognition CHU de Lille University of Lille Inserm France

20. Alzheimer Center and Department of Neurology VU University Medical Center Amsterdam Netherlands

21. Department of Geriatric Psychiatry University Hospital of Psychiatry Zürich Zürich Switzerland

22. Department of Psychiatry Old Age Psychiatry University Hospital of Lausanne Lausanne Switzerland

23. Department of Psychiatry University Hospital of Lausanne Lausanne Switzerland

24. Clinical Drug Development Novo Nordisk Copenhagen Denmark

25. Department of Geriatric Psychiatry Central Institute of Mental Health Medical Faculty Mannheim University of Heidelberg Mannheim Germany

26. School of Medical Sciences Örebro University Örebro Sweden

27. Departments of Geriatrics University Hospital Örebro Örebro Sweden

28. Department of Clinical Science and Education Södertälje Hospital Södersjukhuset Karolinska Institutet Stockholm Sweden

29. Department of Psychiatry University of Oxford Oxford United Kingdom

30. Janssen Medical Ltd High Wycombe United Kingdom

31. Steno Diabetes Center Copenhagen Denmark

32. Institute of Pharmaceutical Sciences King's College London London United Kingdom

33. Department of Radiology and Nuclear Medicine VU University Medical Center Amsterdam Netherlands

34. Queen Square Institute of Neurology and Centre for Medical Image Computing University College London London United Kingdom

35. Department of Psychiatry and Neurochemistry University of Gothenburg Gothenburg Sweden

36. Department of Neurodegenerative Disease UCL Institute of Neurology London United Kingdom

37. Clinical Neurochemistry Laboratory Sahlgrenska University Hospital Mölndal Sweden

38. UK Dementia Research Institute University College London London United Kingdom

39. Hong Kong Center for Neurodegenerative Diseases Hong Kong China

40. Centre for Lifespan Changes in Brain and Cognition University of Oslo Oslo Norway

41. Neurodegenerative Brain Diseases Group VIB Center for Molecular Neurology VIB Antwerp Belgium

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

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