Affiliation:
1. Research School of Chemistry Australian National University Canberra Australian Capital Territory Australia
2. CanTEST Health and Drug Checking Service Canberra Australian Capital Territory Australia
3. Emergency Department Calvary Public Hospital Canberra Australian Capital Territory Australia
4. ANU Medical School Australian National University Canberra Australian Capital Territory Australia
Abstract
AbstractDrug checking is a harm reduction measure that provides people with the opportunity to confirm the identity and purity of substances before consumption. The CanTEST Health and Drug Checking Service is Australia's first fixed‐site drug checking service, where clients can learn about the contents of the samples they provide while receiving tailored harm reduction and health advice. Three samples were recently presented to the service with the expectation of 4‐fluoromethylphenidate (4F‐MPH) 1, methoxetamine (MXE) 2 and 3‐methylmethcathinone (3‐MMC) 3. The identity of all three samples did not meet these expectations and remained unknown on‐site, as no high confidence identifications were obtained. However, further analysis by nuclear magnetic resonance spectroscopy, high resolution gas chromatography‐electron ionisation‐mass spectrometry and liquid chromatography‐electrospray ionisation‐mass spectrometry at the nearby Australian National University allowed for the structure elucidation of the three samples as 4‐fluoro‐α‐pyrrolidinoisohexanophenone (4F‐α‐PiHP) 4, 1‐(4‐fluorobenzyl)‐4‐methylpiperazine (4F‐MBZP) 5 and N‐propyl‐1,2‐diphenylethylamine (propylphenidine) 6, respectively. Given all three samples were not of the expected identity and have not yet been described as new psychoactive substances in the literature, this study presents a full characterisation of each compound. As exemplified by this rapid identification of three unexpected new psychoactive substances, drug checking can be used as an effective method to monitor the unregulated drug market.
Cited by
3 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献