A Dose‐Confirmation Phase 1 Study to Evaluate the Safety and Pharmacology of Glucarpidase in Healthy Volunteers-Reference-Cited by-同舟云学术

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A Dose‐Confirmation Phase 1 Study to Evaluate the Safety and Pharmacology of Glucarpidase in Healthy Volunteers

Published:2021-08-25 Issue: Volume: Page:
ISSN:2160-763X
Container-title:Clinical Pharmacology in Drug Development
language:en
Short-container-title:Clinical Pharmacology in Drug Development

Author:

Fukaya Yutaka¹,Kimura Toshimi¹,Yoshimura Kenichi²,Umemura Kazuo³,Kawamoto Hiroshi⁴

Affiliation:

1. Department of Pharmacy Tokyo Women's Medical University Hospital Tokyo Japan

2. Center for Integrated Medical Research Hiroshima University Hospital Hiroshima Japan

3. Department of Pharmacology Hamamatsu University School of Medicine Hamamatsu Japan

4. Department of Pediatric Oncology National Cancer Center Hospital Tokyo Japan

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpdd.1010

Reference18 articles.

1. The clinical pharmacology of methotrexate.new applications of an old drug

2. The pharmacokinetics of methotrexate and its 7-hydroxy metabolite in patients with rheumatoid arthritis.

3. Population pharmacokinetics of high-dose methotrexate in Japanese adult patients with malignancies: a concurrent analysis of the serum and urine concentration data

4. Drug interaction between celecoxib and methotrexate in organic anion transporter 3–transfected renal cells and in rats in vivo

5. Conversion of methotrexate to 7‐hydroxymethotrexate and 7‐hydroxymethotrexate polyglutamates in cultured rat hepatic cells;Rhee MS;Cancer Res,1986

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Phase 2 study of glucarpidase in patients with delayed methotrexate elimination after high-dose methotrexate therapy;Cancer Chemotherapy and Pharmacology;2024-03-13

2. The use of glucarpidase as a rescue therapy for high dose methotrexate toxicity – a review of pharmacological and clinical data;Expert Opinion on Drug Metabolism & Toxicology;2023-10-20

3. Development of ZD2767P–carboxypeptidase G2–ultrasound therapy against cisplatin-resistant cancer;Frontiers in Oncology;2023-05-18

4. Pharmacokinetics and Pharmacodynamics of Glucarpidase Rescue Treatment After High-dose Methotrexate Therapy Based on Modeling and Simulation;Anticancer Research;2023-04-25

5. Development of a population pharmacokinetics and pharmacodynamics model of glucarpidase rescue treatment after high-dose methotrexate therapy;Frontiers in Oncology;2023-01-30

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