Bombesin receptor subtype-3-expressing neurons regulate energy homeostasis through a novel neuronal pathway in the hypothalamus

Author:

Maruyama Minoru1ORCID,Hotta Natsu1,Nio Yasunori2,Hamagami Kenichi1,Nagi Toshimi3,Funata Masaaki4,Sakamoto Junichi4,Nakakariya Masanori5,Amano Nobuyuki5,Nishida Mayumi6,Okawa Tomohiro3,Arikawa Yasuyoshi3,Sasaki Shinobu7,Kasai Shizuo1,Nagisa Yasutaka1,Habata Yugo1,Mori Masaaki1

Affiliation:

1. Cardiovascular and Metabolic Drug Discovery Unit; Takeda Pharmaceutical Company Limited; Kanagawa Japan

2. Extra Value Generation & General Medicine Drug Discovery Unit; Takeda Pharmaceutical Company Limited; Kanagawa Japan

3. Central Nervous System Drug Discovery Unit; Takeda Pharmaceutical Company Limited; Kanagawa Japan

4. Biomolecular Research Laboratories; Takeda Pharmaceutical Company Limited; Kanagawa Japan

5. Drug Metabolism and Pharmacokinetics Research Laboratories; Takeda Pharmaceutical Company Limited; Kanagawa Japan

6. Integrated Technology Research Laboratories; Takeda Pharmaceutical Company Limited; Kanagawa Japan

7. Medicinal Chemistry Research Laboratories; Pharmaceutical Research Division; Takeda Pharmaceutical Company Limited; Kanagawa Japan

Publisher

Wiley

Subject

Behavioral Neuroscience

Reference60 articles.

1. c-Fos expression in hypothalamic nuclei of food-entrained rats;Angeles-Castellanos;American Journal of Physiology: Regulatory, Integrative and Comparative Physiology,2004

2. Bagnol , D. Grottick , A. J. 2008 G protein-coupled receptor and modulators thereof for the treatment of GABA-related neurological disorders including sleep-related disorders

3. Divergence of melanocortin pathways in the control of food intake and energy expenditure;Balthasar;Cell,2005

4. The dorsomedial hypothalamic nucleus and its role in ingestive behavior and body weight regulation: Lessons learned from lesioning studies;Bellinger;Physiology & Behavior,2002

5. Central injection in rats of α-melanocyte-stimulating hormone analog: Effects on food intake and brain Fos;Brown;Regulatory Peptides,1998

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