Bioactivity-based ultra-performance liquid chromatography-coupled quadrupole time-of-flight mass spectrometry for NF-κB inhibitors identification in Chinese Medicinal Preparation Bufei Granule

Author:

Qingxin Cui1,Min Fu23,Mengge Zhou1,Nianwei Chang4,Ye Pan4,Min Jiang1,Zengtao Sun2,Gang Bai1

Affiliation:

1. State Key Laboratory of Medicinal Chemical Biology and College of Pharmacy; Nankai University; Tianjin 300071 People's Republic of China

2. Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine; Tianjin 300071 People's Republic of China

3. Institute of Basic Research in Clinical Medicine; China Academy of Chinese Medical Sciences; Beijing 100700 People's Republic of China

4. Tianjin University of Traditional Chinese Medicine; Tianjin 300071 People's Republic of China

Funder

Tianjin Research Program of Application and Advanced Technology

National Natural Science Foundation of China

Program of international S&T Cooperation

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference22 articles.

1. Dual-bioactivity-based liquid chromatography-coupled quadrupole time-of-flight mass spectrometry for NF-kappaB inhibitors and beta2AR agonists identification in Chinese Medicinal preparation Qingfei Xiaoyan Wan;Cheng;Analytical and Bioanalytical Chemistry,2012

2. Rapid and global identification of potentially bioactive crude extracts from Chinese medicinal formula chuanbeipipa dropping pills;Dong;Latin American Journal of Pharmacy,2012

3. Bioactivity-integrated ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry for the identification of nuclear factor-kappaB inhibitors and beta2 adrenergic receptor agonists in Chinese medicinal preparation Chuanbeipipa dropping pills;Dong;Biomedical Chromatography,2013

4. Targeting the NF-kappaB pathway in asthma and chronic obstructive pulmonary disease;Edwards;Pharmacology & Therapeutics,2009

5. Formula optimization of the Jiashitang scar removal ointment and antiinflammatory compounds screening by NF-kappaB bioactivity-guided dual-luciferase reporter assay system;Gao;Phytotherapy Research,2015

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