Preparation and purification of 7-Iodoclonazepam for use in Radioimmunoassay
Author:
Publisher
Wiley
Subject
Organic Chemistry,Spectroscopy,Drug Discovery,Radiology, Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry
Reference8 articles.
1. Diazepam: Determination in Micro Samples of Blood, Plasma, and Saliva by Radioimmunoassay
2. Chlordiazepoxide: A New, More Sensitive and Specific Radioimmunoassay
3. Four benzodiazepine radioimmunoassays are described, the most sensitive of which can detect sub-therapeutic levels of bromazepam, chlordiazepoxide, clobazam, demoxepam, desalkylflurazepam, desmethyldiazepam, diazepam, flunitrazepam, lorazepam, medazepam, nitrazepam, oxazepam, prazepam, temazepam and triazolam. The standard curve for diazepam has a concentration range of 0–2·5 ng ml The assay is particularly applicable to blood samples of forensic interest that may be haemolysed or decomposing. A 75 μI sample is required. The antiserum and [3 H]flunitrazepam used are commercially available
4. Preparation of Iodine-131 Labelled Human Growth Hormone of High Specific Activity
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1. Synthesis, Radiosynthesis, and Biological Evaluation of New Proteasome Inhibitors in a Tumor Targeting Approach;Journal of Medicinal Chemistry;2008-02-01
2. Radiosynthesis of no-carrier-added N-(4-dipropyl aminobutyl)-4-[125I]-iodobenzamide, a promising tracer for the detection of melanoma;Journal of Labelled Compounds and Radiopharmaceuticals;1998-10
3. Radiolabeled biotin amides from triazenyl precursors: Synthesis, binding, and in-vivo properties;Journal of Labelled Compounds and Radiopharmaceuticals;1994-12
4. 7-[125I]Iodoclonazepam: Purification by high-performance liquid chromatography for use in a very sensitive benzodiazepine radioimmunoassay of broad specificity;Forensic Science International;1988-10
5. Iodine-125 labeled 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane: an iodinated radioligand that specifically labels the agonist high-affinity state of 5-HT2 serotonin receptors;Journal of Medicinal Chemistry;1988-01
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