PLK4 is upregulated in prostate cancer and its inhibition reduces centrosome amplification and causes senescence-Reference-Cited by-同舟云学术

PLK4 is upregulated in prostate cancer and its inhibition reduces centrosome amplification and causes senescence

Author:

Singh Chandra K.¹^ORCID,Denu Ryan A.²³⁴,Nihal Minakshi¹,Shabbir Maria¹,Garvey Debra R.¹,Huang Wei⁵,Iczkowski Kenneth A.⁶^ORCID,Ahmad Nihal¹⁴⁷^ORCID

Affiliation:

1. Department of Dermatology, School of Medicine and Public Health University of Wisconsin Madison Wisconsin USA

2. Medical Scientist Training Program, School of Medicine and Public Health University of Wisconsin Madison Wisconsin USA

3. Department of Medicine, Division of Hematology/Oncology, School of Medicine and Public Health University of Wisconsin Madison Wisconsin USA

4. Carbone Cancer Center University of Wisconsin Madison Wisconsin USA

5. Department of Pathology and Laboratory Medicine University of Wisconsin Madison Wisconsin USA

6. Department of Pathology Medical College of Wisconsin Milwaukee Wisconsin USA

7. William S. Middleton VA Medical Center Madison Wisconsin USA

Funder

U.S. Department of Veterans Affairs

National Institutes of Health

Publisher

Wiley

Subject

Urology,Oncology

Link

Reference50 articles.

3. Centrosome defects and genetic instability in malignant tumors;Pihan GA;Cancer Res,1998

4. Centrosome defects can account for cellular and genetic changes that characterize prostate cancer progression;Pihan GA;Cancer Res,2001

5. Correlation of centrosomal aberrations with cell differentiation and DNA ploidy in prostate cancer;Toma MI;Anal Quant Cytol Histol,2010

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