DOK3 Modulates Bone Remodeling by Negatively Regulating Osteoclastogenesis and Positively Regulating Osteoblastogenesis
Author:
Affiliation:
1. Department of Medicine; University of Oklahoma Health Science Center; Oklahoma City OK USA
2. Key Laboratory for Zoonosis Research; Jilin University; Changchun China
3. Department of Veterans Affairs; Oklahoma City; OK USA
Funder
National Institutes of Health
Publisher
Wiley
Subject
Orthopedics and Sports Medicine,Endocrinology, Diabetes and Metabolism
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/jbmr.3205/fullpdf
Reference22 articles.
1. Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis;Koga;Nature,2004
2. The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRgamma) regulate development of functional osteoclasts through the Syk tyrosine kinase;Mocsai;Proc Natl Acad Sci U S A,2004
3. Macrophage colony-stimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and beta-catenin;Otero;Nat Immunol,2009
4. TREM2, a DAP12-associated receptor, regulates osteoclast differentiation and function;Humphrey;J Bone Miner Res,2006
5. Osteoimmunology: the expanding role of immunoreceptors in osteoclasts and bone remodeling;Long;Bonekey Rep,2012
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