TCR modifications that enhance chain pairing in gene-modified T cells can augment cross-reactivity and alleviate CD8 dependence-Reference-Cited by-同舟云学术

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TCR modifications that enhance chain pairing in gene-modified T cells can augment cross-reactivity and alleviate CD8 dependence

Published:2018-01-19 Issue:5 Volume:103 Page:973-983
ISSN:0741-5400
Container-title:Journal of Leukocyte Biology
language:en
Short-container-title:J Leukoc Biol

Author:

Spear Timothy T.¹,Foley Kendra C.¹,Garrett-Mayer Elizabeth²³,Nishimura Michael I.¹

Affiliation:

1. Department of Surgery; Cardinal Bernardin Cancer Center; Loyola University Chicago; Maywood Illinois USA

2. Department of Public Health Sciences; Medical University of South Carolina; Charleston South Carolina USA

3. Hollings Cancer Center; Medical University of South Carolina; Charleston South Carolina USA

Funder

National Cancer Institute

Publisher

Wiley

Subject

Cell Biology,Immunology,Immunology and Allergy

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/JLB.5A0817-314R/fullpdf

Reference34 articles.

1. Strategies to genetically engineer T cells for cancer immunotherapy;Spear;Cancer Immunol Immunother,2016

2. Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen;Johnson;Blood,2009

3. T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis;Parkhurst;Mol Ther,2011

4. Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy;Morgan;J Immunother,2013

5. Identification of a titin-derived HLA-A1-presented peptide as a cross-reactive target for engineered MAGE A3-directed T cells;Cameron;Sci Transl Med,2013

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Engineering the T cell receptor for fun and profit: Uncovering complex biology, interrogating the immune system, and targeting disease;Current Opinion in Structural Biology;2022-06

2. Genetic Modification of T Cells for the Immunotherapy of Cancer;Vaccines;2022-03-16

3. Adoptive T-cell Immunotherapy: Perfecting Self-Defenses;Experientia Supplementum;2022

4. The Quest for the Best: How TCR Affinity, Avidity, and Functional Avidity Affect TCR-Engineered T-Cell Antitumor Responses;Cells;2020-07-18

5. Understanding TCR affinity, antigen specificity, and cross-reactivity to improve TCR gene-modified T cells for cancer immunotherapy;Cancer Immunology, Immunotherapy;2019-10-08

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