Sinapic acid mitigates methotrexate‐induced hepatic injuries in rats through modulation of Nrf‐2/ HO ‐1 signaling-Reference-Cited by-同舟云学术

Sinapic acid mitigates methotrexate‐induced hepatic injuries in rats through modulation of Nrf‐2/ HO ‐1 signaling

Published:2021-03-15 Issue:7 Volume:36 Page:1261-1268
ISSN:1520-4081
Container-title:Environmental Toxicology
language:en
Short-container-title:Environmental Toxicology

Author:

Ahmad Ajaz¹^ORCID,Alkharfy Khalid M.¹,Bin Jardan Yousef A.²,Shahid Mudassar²,Ansari Mushtaq Ahmad³,Alqahtani Saeed¹,Jan Basit L.¹,Al‐Jenoobi Fahad I.²,Raish Mohammad²

Affiliation:

1. Department of Clinical Pharmacy, College of Pharmacy King Saud University Riyadh Saudi Arabia

2. Department of Pharmaceutics, College of Pharmacy King Saud University Riyadh Saudi Arabia

3. Department of Pharmacology and Toxicology, College of Pharmacy King Saud University Riyadh Saudi Arabia

Publisher

Wiley

Subject

Health, Toxicology and Mutagenesis,Management, Monitoring, Policy and Law,Toxicology,General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/tox.23123

Reference50 articles.

1. Overview of Dual-Acting Drug Methotrexate in Different Neurological Diseases, Autoimmune Pathologies and Cancers

2. A review of therapeutic challenges and achievements of methotrexate delivery systems for treatment of cancer and rheumatoid arthritis

3. Gastrointestinal and liver side effects of drugs in elderly patients

4. Beneficial effects of Chrysin against Methotrexate-induced hepatotoxicity via attenuation of oxidative stress and apoptosis

5. Methotrexate hepatotoxicity is associated with oxidative stress, and down-regulation of PPARγ and Nrf2: Protective effect of 18β-Glycyrrhetinic acid

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